Rauwolfia Vomitoria Effective Against Pancreatic Cancer Stem Cells

May 2018 – “Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract”

by Ruochen Dong, Ping Chen and Qi Ch
ONCOLOGY REPORTS 40: 3144-3154, 2018.

Rauwolfia Vomitoria Active Against Cancer Stem Cells

In vitro experiments show Rauwolfia vomitoria reducing the number of pancreatic CSCs in a variety of cell lines (see figure below).

Cancer Stem Cells and Rauwolfia Vomitoria in vitro

As the amount of Rauwolfia vomitoria is increased, the number of pancreatic cancer stem cells drastically decreases.

Even more impressive, the in vivo data demonstrates that Rauwolfia counteracts the defining behavior of CSCs, their ability to promote formation and growth of new pancreatic tumors. The charts below show how the single Rauwolfia treatment significantly inhibited the tumor formation rate (C) and the size of formed tumors (D).

Cancer Stem Cells and Rauwolfia Vomitoria in vivo

The researchers at Kansas University Medical Center concluded that, much like Pao pereria, Rauwolfia vomitoria also holds great promise as a novel treatment for targeting pancreatic CSCs. The two natural extracts are a vital method of treatments that are bringing new, real cancer cures.

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Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract

Posted in Our Research Publications, Pancreatic Cancer and tagged , , , .